Botox once was well known as a beauty therapy is being considered by the researchers from Norway, Japan, Germany and the US, as a cheap, safe and effective anti-cancer treatment.
The researchers found that the nervous system particularly the vegal nerve has an a role in cancer by contributing to the growth of gastric tumors through the release of a neurotransmitter.
According to Prof. Duan Chen, of the Norwegian University of Science and Technology, confirmed that the removal of effect of the vagal nerve (nerve that contributes to the growth of gastric tumors through the release of a neurotransmitter.), the stem cells in the cancer tumor are suppressed, and leading to cancer treatment and prevention.
The administering of a local injection of Botox to block the release of the neurotransmitter from the vagus nerve was one among the trialed four methods (vagotomy, injecting a drug to block the receptor of the neurotransmitter and knocking out the receptor gene) by the team to sever connections between the nerve and tumor, is profoundly a good treatment because it can be used locally and it targets the cancer stem cells, less expensive and less toxic than most standard cancer treatments, with hardly any side effects.
According to the co-author Prof. Timothy C. Wang, of Columbia University Medical Center, NY, confirmed that Botox has been successfully used in the past to block acetylcholine release from nerve terminals - that is how it paralyzes facial muscles, in gastroenterology (to relax tight sphincters in the esophagus and stomach), and to reduce the growth of enlarged prostates in men.
Read original article "Gastric cancer: could Botox be an alternative to chemo?"